Dr.
Anthony P. Cheung
MD, MPH, MBA, FRANZCOG, FRCSC
Clinical Professor
Division of Reproductive Endocrinology and Infertility
Provincial Health Services Authority (PHSA)
BC Women's Hospital
acheung@fertilitywithgrace.com
: 6045584886
Biography
Dr. Cheung is Clinical Professor, UBC Department of Obstetrics & Gynaecology (the Department). Dr. Cheung is an Associate Clinician-Scientist at Child and Family Research Institute (CFRI) of BC.
Dr. Cheung received his MD from the University of Sydney, Australia. After completing subspecialty training in Menopause at the Centre for the Management of Menopause in Sydney, Australia and Reproductive Endocrinology and Infertility (REI) at the University of California, Davis, CA, he became a Faculty member in the Department of Obstetrics and Gynaecology at the University of Alberta, 1992-1996. In 1996, Dr Cheung joined UBC.
Dr.Cheung has published many peer-reviewed scientific papers and conference proceedings and is a frequent, invited reviewer for scientific journals and research granting agencies.
Dr Cheung is an active member of the Graduate Program in Reproductive and Developmental Sciences of the Department. He teaches and mentors students at all levels – undergraduate, postgraduate, and post-doctoral and trains specialty physician residents and fellows in GREI. He sits on many PhD supervisory committees, and is a frequent UBC examiner for PhD candidature examination and thesis defence. He is a popular course organizer and speaker in continuing medical education (CME) events for practicing physicians for the Society of Obstetricians and Gynaecologists of Canada (SOGC).
Teaching
Research Interests/Skills
Publications
Cheung AP, Chang RJ. Polycystic ovary syndrome. Clin Obstet Gynecol 1990; 33: 655-667.
Schindler M, Gatt S, Isert P, Morgans D, Cheung A. Thrombocytopenia and platelet functional defects in pre-eclampsia: implications for regional anaesthesia. Anaesth Intens Care 1990; 18: 169-174.
Cheung AP, Wren BG. A cost-effectiveness analysis of hormone replacement in the menopause. Med J Aust 1992; 156: 312-316.
Erickson GF, Magoffin DA, Garzo VG, Cheung AP, Chang RJ. Granulosa cells of polycystic ovaries: are they normal or abnormal? Human Reproduction 1992; 7: 293-299.
Cheung AP. Clinical approach to female reproductive problems. Occupational Medicine: State of the Art Reviews 1994; 9: 415-422. Hanley & Belfus, Inc., Philadelphia.
Cheung AP, Chang RJ. Pituitary responsiveness to gonadotropin-releasing hormone agonist stimulation: a dose-response comparison of LH/FSH secretion in women with polycystic ovary syndrome and normal women. Human Reproduction 1995; 4: 1054-1059.
Xu X, Seth PC, Harbison DS, Cheung AP, Foxcroft GR. Semen dilution for assessment of boar ejaculate quality in pig IVM and IVF system. Theriogenology 1996; 46:1325-1337.
Cheung AP, Lu JK, Chang RJ. Pulsatile gonadotropin secretion in women with polycystic ovary syndrome after GnRH agonist treatment. Human Reproduction 1997; 12: 1156-1164.
Cheung A.P. Commentary: Two fixed dose regimens of recombinant FSH in ovarian stimulation for IVF. In: “Journal Club in Reproductive Medicine, www.Ferti.net, ed. Prof. dr. Salim Daya”, December, 1999.
Steigrad SJ, Cheung AP, Osborn RA. Choriocarcinoma co-existent with an intact pregnancy: case report and review of the literature. J Obstet Gynaecol Res 1999; 25:197-203.
Cheung A.P. Commentary: Comparing recombinant hCG with urinary hCG when used in ART cycles. In: “Journal Club in Reproductive Medicine, www.Ferti.net, ed. Prof. dr. Salim Daya”, December, 2000.
Motamed KA, Cheung AP, Lee CY. Mechanisms of cholesterol inhibitory effects on progesterone-induced acrosome reaction of human sperm. Journal of Andrology 2000; 21: 586-94.
Cheung AP. Acute effects of estradiol and progesterone on insulin, lipids and lipoproteins in postmenopausal women: a pilot study. Maturitas 2000; 35: 45-50.
Cheung AP. Ultrasound and menstrual history in predicting endometrial hyperplasia in women with polycystic ovary syndrome. Obstet Gynecol 2001; 98:325-31.
Awatani K, Cheung AP. Metformin and polycystic ovary syndrome: a literature review. JOGC 2002; 24:393-401.
Cheung AP, Pride SM, Ho Yuen B, Sy L. In vivo ovarian androgen responses to recombinant follicle stimulating hormone (FSH) with and without recombinant luteinizing hormone (LH) in polycystic ovary syndrome (PCOS). Human Reproduction 2002 17:2540-7
Lee, C-Y, Loutet S, Classen D, Cheung AP. A semi-quantitative rapid test for C-reactive protein. Journal of Clinical Ligand Assay 2003; 26:37-41.
Chow V, Cheung AP. Investigation of male infertility. Journal of Reproductive Medicine 2004.
Lee GCY, Zheng GX, Lin X, Cheung AP. Semi-quantitative immunochromatographic assays. Journal of Clinical Ligand Assay 2004.
Tan SL, Child TJ, Cheung AP, Fluker M, Yuzpe A, Casper R, Leung P, Cadesky K, Davis VJ. A randomized, double-blind, multicentre study comparing a starting dose of 100 IU or 200 IU of recombinant follicle stimulating hormone (Puregon)
Cheung AP. Assisted Reproductive Technologies and perinatal outcomes. Journal of Reproductive Medicine 2004.
Shi F, Cheung AP, Leung PCK. Growth differentiation factor 9 (GDF9) enhances activin A-induced inhibin B and subunits in human luteinized granulosa cells (submitted to JCEM, under review)
K. Huang Q, Cheung AP, Zhang Yu, et al. Effects of growth differentiation factor 9 (GDF-9) on cell cycle regulators and ERK 42/44 in human granulosa cell proliferation. (submitted to AJP, under review)
Vause T, Cheung AP. Ovulation induction in polycystic ovary syndrome. (Clinical Guidelines) J Obstet Gynaecol Can
Ho Yuen B, Nguyen TA, Cheung AP, et al. 2008 Clinical and endocrine response to the withdrawal of gonadotropin-releasing hormone agonists during prolonged coasting. Fertility and sterility
Hong IS, Cheung AP, Leung PC 2008 Gonadotropin-releasing hormones I and II induce apoptosis in human granulosa cells. The Journal of clinical endocrinology and metabolism 93:3179-3185
Cheung AP, Gysler M, Leader A, Hughes E. Informed consent to donate embryos for research purposes. J Obstet Gynaecol Can 2009;31;111; author reply -2.
Ho Yuen B, Nguyen TA, Cheung AP, Leung PC. Clinical and endocrine response to the withdrawal of gonadotropin-releasing hormone agonists during prolonged coasting. Fertil Steril 2009;92:499-507.
Huang Q. Cheung AP, Zhang Y, Huang HF, Auersperg N, Leung PC. Effects of growth differentialtion factor 9 on cell cycle regulators and ERK42/44 in human granulosa cell proliferation. Am J Physiol Endocrinol Metab 2009;296:E1344-53.
Shi FT, Cheung AP, Huang HF, Leung PC. Effects of Endogenous Growth Differentiation Factor 9 on Activin A-Induced Inhibin B Production in Human Granulosa-Lutein Cells. J Clin Endocrinol Metab 2009.
Shi FT, Cheung AP, Leung PC. Growth differentiation factor 9 enhances activin a-induced inhibin B production in human granulosa cells. Endocrinology 2009;150:3540-6.
Cheung AP. Polycystic ovary syndrome: a contemporary view. J Obstet Gynaecol Can 2010 32(5):423-5, 6-8.
Vause TDR, Cheung AP. Ovulation induction in polycystic ovary syndrome. J Obstet Gynaecol Can 2010 32(5):495-502. (Senior author and principal co-writer).
Cheung AP, Chang RJ. Polycystic ovaries and other causes of hyperandrogenism. Infert Repro Med Clin of North America 1991; 2:465-477.
Cheung AP, Lu JHK, Chang RJ. Hypothalamic-pituitary dynamics in polycystic ovary syndrome. In: Chang RJ, ed. Polycystic ovary syndrome, Serono Symposia USA. New York: Springer, 1996: 254-264.
Cheung AP. Cost-effectiveness of hormone replacement therapy. In Wren BG, Nachtigall LE, eds. Clinical management of the menopause. Sydney: McGraw-Hill, 1996:141-147.
Grants
CIHR – The role of women’s knowledge and beliefs about ART in their decisions to delay childbearing
PI: Daniluk, Judith, PhD, Counselling Psychology Co: A Cheung
Defining a more predictive reference for sperm parameters in semen analysis for our comptemporary BC male population, BC Medical Services Foundation, $39,944, 1999-2001, A Cheung PI.
Establishing a Canadian registry for the study of polycystic ovary syndrome, Canadian Foundation for Women’s Health, $25,000, 2004-2004, A Cheung PI, S Pride & S Gill CIs.
Validation of molimina by questionnaires as an indicator of ovulation for population-based studies, CIHR, $100,000, 2005-2006, J Prior PI, A Cheung CI.
Environmental factors on human fertility and reproductive outcomes, CIHR, $10,000, 2009-2009, A Cheung PI.
Noninvasive assessment of embryo quality in human in vitro fertilization: metabolomic profiling of embryo culture media with Raman spectroscopy, WHRI. $25,000, 2009-2010, A Cheung PI.
The role of women’s knowledge and beliefs about ART in their decisions to delay childbearing, CIHR, $70,575, J Daniluk PI, A Cheung CI.